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Publications


2017
 

The Potential of Indonesian Gastropods found around Bunaken Island for Production of Bioactive Compounds. K. M. Fisch, C. Hertzer, N. Böhringer, Z. G. Wuisan, D. Schillo, R. Bara, F. Kaligis,H. Wägele, G. M. König, T. F. Schäberle. Mar. Drugs, 2017, 15, 384.

Diversity and antimicrobial potential of predatory bacteria from the peruvian coastline. L. Linares-Otoya, V. Linares-Otoya, L. Armas-Mantilla, C. Blanco-Olano, M. Crüsemann, M. L. Gonoza-Yupanqui, J. Campos-Florian, G. M. König, T. F. Schäberle. Marine Drugs, 2017, 15, 308.

 
Identification and heterologous expression of the kocurin biosynthetic gene cluster. L. Linares-Otoya, V. Linares-Otoya, L. Armas-Mantilla, C. Blanco-Olano, M. Crüsemann, M. L. Gonoza-Yupanqui, J. Campos-Florian, G. M. König, T. F. Schäberle. Microbiologie, 2017, 163, 1409-1414.
 
The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation. C. S. N. Klose, T. Mahlakõiv, J. B. Moeller, L. C. Rankin, A.-L. Flamar, H. Kabata, L. A. Monticelli, S. Moriyama, G. Garbès Putzel, N. Rakhilin, X. Shen, E. Kostenis, G. M. König, T. Senda, D. Carpenter, D. L. Farber, D. Artis. Nature, 2017, 549, 282-286.
 
Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma. M. Matthey, R. Roberts, A. Seidinger, A. Simon, R. Schröder, M. Kuschak, S. Annala, G. M. König, C. E Müller, I. P Hall, E. Kostenis, B. K. Fleischmann, D. Wenzel. Science Translational Medicine; DOI: 10.1126/scitranslmed.aag2288
 

Reactivation of Gai-coupled formyl peptide reecptors is inhibited by Gaq-selctive inhibitors when induced by signals generated by the platelet-activating factor receptor. A. Holdfeldt, R. A. Dahlstrand, M. Gabl, Z. Rajabkhani, G. M. König, E. Kostenis, C. Dahlgren, H. Forsman. J. Leukoc. Biol. 2017, 102, 871-880.

 
Volatiles from the fungal microbiome of the marine sponge Callyspongia cf. flammea. L. Barra, P. Barac, G. M. König, M. Crüsemann, J. S. Dickschat, Org. Biomol. Chem., 2017, 15, 7411-7421.
 
Draft genome sequence of Zobellia sp. OII3, isolated from the coastal zone of the baltic sea. H. Harms, A. Poehlein, A. Thürmer, G. M. König, T. F. Schäberle. Genome Announc., 2017, 5, e00737-17.
 
Biosynthetic studies on acetosellin and structure elucidation of a new acetosellin derivative. P. Hufendiek, S. S. M. Stölben, H. Harms, S. Kehraus, N. Merten, M.Crüsemann, I. Arslan, M. Gütschow, T. Schneider, G.M. König. Planta Medica, 2017, 83, 1044-1052.

Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6. A. Brüser, A. Zimmermann, B. C. Crews, G. Sliwoski, J. Meiler, G. M. König, E. Kostenis, V. Lede, L. M. Marnett, T. Schöneberg. Scientific Reports, 2017, 7, 2380.

Antimicrobial potential of bacteria associated with marine sea slugs from North Sulawesi, Indonesia. N. Böhringer, K. M. Fisch, D. Schillo, R. Bara, C. Hertzer, F. Grein, J.-H. Eisenbarth, F. Kaligis, T. Schneider, H. Wägele, G. M. König, T. F. Schäberle. Front. Microbiol., 2017, 8, 1092.


Secondary metabolome and its defensive role in the aeolidoidean Phyllodesmium longicirrum, (Gastropoda, Heterobranchia, Nudibranchia). A. Bogdanov, C. Hertzer, S. Kehraus, S. Nietzer, S. Rohde, P. J. Schupp, H. Wägele, G. M. König.  Beilstein J. Org. Chem., 2017, 13, 502-519.
 
The rare amino acid building block 3-(3-furyl)-alanine in the the formation of non-ribosomal peptides. F. El Maddah, M. Nazir, G. M. König. Nat. Prod. Commun. 2017, 12, 147-150.


Phileucin - a cyclic dipeptide similar to phevalin (aureusimine B) from Streptomyces coelicolor M1146. N. Böhringer, M. Gütschow, G. M. König, T. F. Schäberle. Nat. Prod. Commun. 2017, 12, 107-109.


Production of antimicrobial compounds by fermentation. Harms H., König G.M., Schäberle T.F.. Methods in Molecular Biology, 2016, 1520, 49-61.


2016


Insights into the biosynthetic origin of 3-(3-furyl)alanine in Stachylidium sp. 293 K04 tetrapeptides. F. El Maddah, S.. Kehraus, M. Nazir, C. Almeida, G. M. König. J. Nat. Prod., 2016, 79, 2838-2845.


A novel allosteric activator of free fatty acid 2 receptor displays unique Gi-functional bias. D. Bolognini, C. E. Moss, K. Nilsson, A. U. Petersson, I. Donnelly, E. Sergeev, G. M. König, E. Kostenis, M. Kurowska-Stolarska, A. Miller, N. Dekker, A. B. Tobin, G. Milligan. J. Biol. Chem., 2016, 291, 18915-18931.


The adhesion G protein-coupled receptor GPR56/ADGRG1 is an inhibitory receptor on human NK cells. Chang, G. W., Hsiao, C. C., Peng, Y. M., Vieira Braga,  F. A., Kragten, N. A., Remmerswaal, E. B., van de Garde, M. D., Straussberg, R., König, G. M., Kostenis, E., Knäuper, V., Meyaard, L., van Lier, R. A., van Gisbergen, K. P., Lin,  H. H., Hamann, J. Cell. Rep., 2016, 15, 1-15.

Marine-derived myxobacteria of the suborder Nannocystineae: An underexplored source of structurally intriguing and biologically active metabolites. A. Dávila-Céspedes, P. Hufendiek, M. Crüsemann, T. F. Schäberle, G. M. König. Beilstein J. Org. Chem., 2016, 12, 969-984.

Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction. S.J. Bradley, C.H. Wiegman, M.M. Iglesias, K.C. Kong, A.J. Butcher, B. Plouffe, E. Goupil, J.-M. Bourggognon, T. Macedo-Hatch, C. LeGouill, K. Russell, S.A. Laporte, G.M. König, E. Kostenis, M. Bouvier, K.F. Chung, Y. Amrani, A.B. Tobin. PNAS, 2016, 113, 4524-4529.

Genome reduction and synthesis of secondary metabolites in Candidatus Burkholderia crenata, the obligate leaf nodule symbiont of Ardisia crenata Sims. A. Carlier, L. Fehr, M. Pinto, T.F. Schäberle, R. Reher, S. Dessein, G.M. König, L. Eberl. Environ. Microbiol. 2016, 18, 2507-2522.

Defensive diterpene from the Aeolidoidean Phyllodesmium longicirrum. A. Bogdanov, C. Hertzer, S. Kehraus, S. Nietzer, S. Rohde, P. J. Schupp, H. Wägele, G. M. König. J. Nat. Prod., 2016, 79, 611-615.

The Gq signalling pathway inhibits brown and beige adipose tissue. K. Klepac, A. Kilic, T. Gnad, L. M. Brown, B. Herrmann, A. Wilderman, A. Balkow, A. Glöde, K. Simon, M. E. Lidell, M. J. Betz, S. Enerbäck, J. Wess, M. Freichel, M. Blüher, G. König, E. Kostenis, P. A. Insel, A. Pfeifer. Nature Commun.,2016, 7:10895.

Endolides A and B, vasopressin and serotonin-receptor interacting N-methylated peptides from the sponge-derived fungus Stachylidium sp.  C. Almeida, F. El Maddah, S. Kehraus, G. Schnakenburg, G. M. König. Org. Lett., 2016, 18, 528-531.


2015

The experimental power of FR900359 to study Gq-regulated biological processes. Ramona Schrage, Anna-Lena Schmitz, Evelyn Gaffal, Suvi Annala, Stefan Kehraus, Daniela Wenzel, Katrin M. Bullesbach, Tobias Bald, Asuka Inoue, Yuji Shinjo, Segolene Galandrin, Naveen Shridhar, Michael Hesse, Manuel Grundmann, Nicole Merten, Thomas H. Charpentier, Matthew Martz, Adrian J. Butcher, Tanja Slodczyk, Sylvain Armando, Maike Effern, Yoon Namkung, Laura Jenkins, Velten Horn, Anne Stoel, Harald Dargatz, Daniel Tietze, Diana Imhof, Celine Gales, Christel Drewke, Christa E. Muller, Michael Holzel, Graeme Milligan, Andrew B. Tobin, Jesus Gomeza, Henrik G. Dohlman, John Sondek, T. Kendall Harden, Michel Bouvier, Stephane A. Laporte, Junken Aoki, Bernd K. Fleischmann, Klaus Mohr, Gabriele M. König, Thomas Tüting, Evi Kostenis. Nature Commun., 2015, 6:10156.

Aß-42 lowering agents from the marine.derived fungus Dichotomomyces cejpii. H. Harms, S. Kehraus, D. Nesaei-Mosaferan, P. Hufendiek, L. Meijer, G. M. König. Steroids, 2015, 104, 182-188.

Harnessing enzymatic promiscuity in myxochelin biosynthesis for the production of 5-lipoxygenase inhibitors. J. Korb, S. König, S. Schieferdecker,  H.M. Dahse, G.M. König, O. Werz, M. Nett. ChemBioChem, 2015, 16, 2445-2450.

Insights into structure-activity relationships of bacterial RNA polymerase inhibiting corallopyronin derivatives. T. F. Schäberle, A. Schmitz, G. Zocher, A. Schiefer, S. Kehraus, E. Neu, M. Roth, D. G. Vassylyev, T. Stehle, G. Bierbaum, A. Hörauf, K. Pfarr, G. M. König. J. Nat. Prod. , 2015, 78, 2505-2509.

GPR18 inhibiting amauromine and the novel triterpene glycoside auxarthonoside from the sponge-derived fungus Auxarthron reticulatum. M. Nazir, H. Harms, I. Loef, S. Kehraus, F. El Maddah, I.Arslan, V. Rempel, C.E. Müller, G.M. König. Planta Medica, 2015, 81, 1141-1145.

Epipolythiodiketopiperazines form the marine-derived fungus Dichotomomyces cejpij with NF-kB inhibitory potential. H. Harms, B. Orlikova, S. Ji, D. Nesaei-Mosaferan, G.M. König, M. Diederich. Marine Drugs, 2015, 13, 4949-4966.

Phenalenones: insight into the biosynthesis of polyketides from the marine alga-derived fungus Coniothyrium cereale. M. Nazir, F. El Maddah, S. Kehraus, E. Egereva, J. Piel, A..O. Brachmann, G.M. König. Org. Biomol. Chem., 2015, 13, 8071-8079.

New bicyclo-spartinols from the marine-derived fungus Phaeosphaeria spartinae. M. F. Elsebai, F. El Maddah, S. Kehraus, G. M. König, Nat. Prod. Com., 2015, 10, 637-639.


2014

Combining metabolomic analysis and microarray gene expression analysis in the charcterization of the medicinal plant Chelidonium majus L. A. Orland, K. Knapp, G.M. König, G. Ulrich.Merzenich, W. Knöß. Phytomedicine 2014, 21, 1587-1596.

Differential transcriptional profiles in HepG2 cells after the exposure to a chemically characterized complex preparation of Silybi mariani fructus and its chemically defined constituents silybin A + B. A. Orland, K. Knapp, G.M. König, W. Knöss, G. Ulrich-Merzenich. Synergy 2014, 1, 99-108.

Defense in the aeolidoidean genus Phyllodesmium (Gastropoda). A. Bogdanov, S. Bleidissel, G. Preisfld, D. Schillo, J. Piel, A.O. Brachmann, H. Wägele, G.M. König. J. Chem. Ecol. 2014, 40, 1013-1024.

Function of the loading module in CorI and of the O-methyltransferase CorH in vinyl carbamate biosynthesis of the antibiotic corallopyronin A. T. F. Schäberle, M. Mir Mohseni, F. Lohr, A. Schmitz, G. M. König. Antimicrob. Agents Chemother. 2014, 58, 950-956.

Antibiotics from Myxobacteria. T. F. Schäberle, F. Lohr, A. Schmitz, G. M. König. Nat. Prod. Rep., 2014, 31, 953-972.

Enhanced production of undecylprodigiosin in Streptomyces coelicilor by co-cultivation with the corallopyronin A-producing myxobacterium Corallococcus coralloides. T. F. Schäberle, A. Orland, G. M. König. Biotech. Lett., 2014, 36, 641-648.

Indoloditerpenes from a marine.derived fungal strain of Dichotomomyces cejpii with antagonistic activity at GPR18 and cannabinoid receptors. H. Harms, V. Rempel, S. Kehraus, M. Kaiser, P. Hufendiek, C. E. Müller, G. M. König, J. Nat. Prod., 2014, 77, 673-677.

Biosynthesis of phenylnannolone A, a multidrug resistance reversal agent from the halotolerant myxobacterium Nannocystis pusilla B150. S. M Bouhired, M. Crüsemann, C. Almeida, T. Weber, J. Piel, T. F. Schäberle, G. M. König. ChemBioChem, 2014, 15, 757-765.

Identification of sequestered chloroplasts in photosynthetic and non-photosynthetic sacoglossan sea slugs (Mollusca, Gastropoda). G. Christa, K. Händeler, T. F. Shäberle, G. M. König, H. Wägele. Frontiers in Zoology, 2014, 11, 15.

Corallorazines from the myxobacterium Corallococcus coralloide. A. Schmitz, S. Kehraus, T.F. Schäberle, E. Neu, C. Almeida, M. Roth, G. M. König, J. Nat. Prod., 2014, 77, 159-163.

Corallopyronin A – A promising antibiotic for treatment of filariasis. T.F. Schäberle, A. Schiefer, A. Schmitz, G.M. König, A. Hörauf, K. Pfarr. International Journal of Medical Microbiology, 2014, 304, 72-78.


2013

Decoding signaling and function of the orphan G protein–coupled receptor GPR17 with a small-molecule agonist. S. Hennen, H. Wang, L. Peters, N. Merten, K. Simon, A. Spinrath, S., R. Akkari, R. Schrage, R. Schröder, D. Schulz, C.Vermeiren, K. Zimmermann, S. Kehraus, C. Drewke, A. Pfeifer, G.M. König, K. Mohr, M. Gillard, C.E. Müller, Q.R. Lu, J. Gomeza, E. Kostenis. Science Signal. 2013, 6, ra93.

Double bond migration in corallopyronin A biosynthesis. F. Lohr, I. Jenniches, M. Frizler, M. J. Meehan, M. Sylvester, A. Schmitz, M. Gütschow, P. C. Dorrestein, G. M. König, T. F. Schäberle. Chem. Sci. 2013, 4, 4175-4180.

Antibiotics from gliding bacteria. A. Schmitz, S. Felder, T. Höver, S. Kehraus, E. Neu, F. Lohr, G.M. König, T.F. Schäberle. Phytochemistry Reviews, 2013, 12, 507-516.

Salimyxins and Enhygrolides: Antibiotic, sponge-related metabolites from the obligate marine myxobacterium Enhygromyxa salina. S. Felder, S. Kehraus, E. Neu, G. Bierbaum, T. F. Schäberle, G. M. König. ChemBioChem, 2013, 14, 1363-1371.

Salimabromide: Unexpected chemistry from the obligate marine myxobacterium Enhygromyxa salina: S. Felder, S. Dreisigacker, S. Kehraus, E. Neu, G. Bierbaum, P. R. Wright, D. Mneche, T. F. Schäberle, G. M. König, Chem. Eur. J., 2013, 19, 9319-9324.

Caught between triterpene- and steroid-metabolism: 4a-carboxylic pregane-derivative from the marine alga-derived fungus Phaeosphaeria spartinae. M. F. Elsebai, S. Kehraus, G. M. König, Steroids, 78, 880-883.

Unprecedented polyketides from a marine sponge-associated Stachylidium sp. C. Almeida, E. Egereva, S. Kehraus, G. M. König, J. Nat. Prod., 2013, 76, 322-326.

What remains after 2 months of starvation? Analysis of sequestered algae in a photosynthetic slug, Plakobranchus ocellatus (Sacoglossa, Opistobranchia), by barcoding. G. Christa, L. Wescott, T. F. Schäberle, G. M. König, H. Wägele, Planta, 2013, 237, 559-572.

An easy-to-perform photometric assay for methyltransferase activity measurements. T. F. Schäberle, C. Siba, T. Höver, G. M. König, Anal. Biochem, 2013, 432, 38-40.

 

2012

New insight into the biosynthesis of prenylated xanthones: Xptb from Aspergillus nidulans catalsyses an O-prenylation of xanthones. D. Pockrandt, L. Ludwig, A. Fan, G. M. König, S.-M. Li, ChemBioChem, 2012, 13, 2764-2771.
 

Polyketide skeletons from the marine alga-derived fungus Coniothyrium cereale. M. F. Elsebai, M. Nazir, S. Kehraus, E. Egereva, K. Ndjoko loset, L. Marcourt, D. Jeanerat, M. Gütschow, J.-L. Wolfender, G. M. König, Eur. J. Org. Chem, 2012, 6197-6203.

Marilines A-C: Novel phthalimidines from the sponge-derived fungus Stachylidium sp. C. Almeida, Y. Hemberger, S. M. Schmitt, S. Bouhired, L. Natesan, S. Kehraus, K. Dimas, M. Gütschow, G. Bringmann, G. M. König, Chem. Eur. J., 2012, 18, 8827-8834.

Corallopyronin A specifically targets and depletes essential obligate Wolbachia endobacteria from filarial nematodes in vivo. A. Schiefer, A. Schmitz, T.  F. Schäberle, S. Specht, C. Lämmer, K. L. Johnston, D. G. Vassylyev, G. M. König, A. Hoerauf, K. Pfarr, J. Inf. Dis., 2012, 206, 249-257.

4-Hydroxyphenylglycine biosynthesis in Herpetosiphon aurantiacus: a case of gene duplication and catalytic divergence. S. Kastner, S. Müller, L. Natesan, G. M. König, R. Guthke, M. Nett  Arch. Microbiol., 2012, 194, 557-566.

 

2011

Marilones A-C, phthalides from the sponge derived fungus Stachylidium sp. C. Almeida, S. Kehraus, M. Prudencio, G. M. König, Beilstein J. Org. Chem., 2011, 7, 1636-1642.

Identifikation of a potent and selective cannabinoid CB1 receptor antagonist from Auxarthron reticulatum. M.F. Elsebai, V. Rempel, G. Schnakenburg, S. Kehraus, C.E. Müller, G.M. König, ACS. Med. Chem. Lett., 2011, 2, 866-869.

HLE-inhibitory alkaloids with a polyketide skeleton from the marine-derived fungus Coniothyrium cereale. M. F. Elsebai, L. Natesan, S. Kehraus, G. Schnakenburg, F. Sasse, S. Shaaban, M. Gütschow, G. M. König, J. Nat. Prod., 2011, 74, 2282-2285.

Dotofide, a guanidine-interrupted terpenoid from the marine slug Doto pinnatifida (Gastropoda, Nudibranchia). A. Putz,  S. Kehraus, G. Diaz-Agras, H. Wägele, G. M. König, Eur. J. Org. Chem., 2011, 3733-3737.

Stachyline A-D from the sponge derived fungus Stachylidium sp. C. Almeida, N. Part, S. Bouhired, S. Kehraus, G. M. König, J. Nat. Prod., 2011, 74, 21-25.

Antimicrobial phenalenone derivatives from the marine-derived fungus Coniothyrium cereale. M. F. Elsebai, S. Kehraus, U. Lindequist, F. Sasse, S. Shaaban, M. Gütschow, M. Josten, H.-G. Sahl, G. M. König, Org. Biomol. Chem., 2011, 9, 802-808.

 

2010

Mode of action of epoxyphomalins A and B and characterization of related metabolites from the marine-derived fungus Paraconiothyrium sp. I. E. Mohamed, S. Kehraus, A. Krick, G. M. König, G. Kelter, A. Maier, H.-H. Fiebig, M. Kalesse, N.P. Malek, H. Gross, J. Nat. Prod., 2010, 73, 2053-2056.

Fungal metabolites: structural diversity as incentive for anticancer drug development. H. Greve, I. E. Mohamed, A. Pontius, S. Kehraus, H. Gross, G. M. König, Phytochem. Rev., 2010, 9, 537-545.

Defensive strategies of Cladobranchia (Gastropoda, Opisthobranchia). A. Putz, G. M. König, H. Wägele, Nat. Prod. Rep. , 2010, 27, 1386-1402.

Marine myxobacteria as a source of antibiotics - comparison of phylogy, polyketide-type genes and antibiotic production of three isolates of  Enhygromyxa salina. T. F. Schäberle, E. Goralski, E. Neu, G. Hölzl, P. Dörmann, G. Bierbaum, Ö. Erol, G.M. König, Mar. Drugs, 2010, 8, 2466-2479.

Spartinoxide, a new enantiomer of A82775C with inhibitory activity toward HLE from the the marine-derived fungus Phaeosphaeria spartinae. M. F. Elsebai, S. Kehraus, M. Gütschow, G. M. König, Nat. Prod. Com., 2010, 5, 1071-1076.

Synergistic allelochemicals from a freshwater cyanobacterium. P.N. Lao, A.R. Pereira, W.-T. Liu, J. Ng, P.A. Pevzner, P.C. Dorrestein, G.M. König, V.M. Vasconcelos, W.H. Gerwick , PNAS, 2010, 107, 11183-11188.

Biosynthesis of the myxobacterial antibiotic Corallopyronin A. Ö. Erol, T. F. Schäberle, A. Schmitz, S. Rachid, C. Gurgui, M. El Omari, F. Lohr, S. Kehraus, J. Piel, R. Müller, G. M. König, ChemBioChem, 2010, 11, 1253-12665.

Novel bisabolane sesquiterpenes from the marine-derived fungus Verticilium tenerum. C. Almeida, S. Elsaedi, S. Kehraus, G. M. König, Nat. Prod. Com., 2010, 5, 507-510.

Hydroxylated sclerosporin derivatives from the marine-derived fungus Cadophora malorum. C. Almeida, E. Eguereva, S. Kehraus, C. Siering, G. M. König, J. Nat. Prod., 2010, 73, 476-478.

In vitro chemopreventive potential of fucophlorethols from the brown alga Fucus vesiculosus L. by anti-oxidant activity and inhibition of selected cytochrome P450 enzymes. S. Parys, S. Kehraus, A. Krick, K.-W. Glombitza, S. Carmeli, K. Klimo, C. Gerhäuser, G. M. König, Phytochemistry, 2010, 71, 221-229.

 

2009

New Polyketides from the marine-derived fungus Phaeosphaeria spartinae, M.F. Elsebai, S. Kehraus, M. Gütschow, G. M. König, Nat. Prod. Com., 2009, 4, 1463-1468.

Epoxyphomalin A and B, prenylated polyketides with potent cytotxicity from the marine-derived fungus Phoma sp., Org. Lett., 2009, 11, 5014-5017.

Inhibition of human leukocyte elastase by brunsvicamides A-C: Cyanobacterial cyclic peptides. M. T. Sisay, S. Hautmann, C. Mehner, G. M. König, J. Bajorath, M. Gütschow, ChemMedChem, 2009, 4, 1425-1429.

Seasonal variation of polyphenolics in Ascophyllum nodosum (Phaeophyceae). S. Parys, S. Kehraus, R. Pete, F. C. Küpper, K.-W. Glombitza, G. M. König, Europ. J. Phycol., 2009, 44, 331-338.

The superhydrophilic and superoleophilic leaf surface of Ruellia devosiana (Acanthaceae): a biological model for spreading of water and oil on surfaces. K. Koch, I. C. Blecher, G. M. König, S. Kehraus, W. Barthlott, Funct. Plant. Biol., 2009, 36, 339-350.

Biohalogenation: Nature's way to synthesize halogenated metabolites; C. Wagner, M. El-Omari, G. M. König, J. Nat. Prod., 2009, 72, 540-553.

Three new spongian diterpenes from the Fijian marine sponge Spongia sp., H. Gross, A. D. Wright, U. Reinscheid, G. M. König, Nat. Prod. Com., 2009, 4, 315-322.

Cytotoxic and HLE-inhibitory tetramic acid derivatives from marine derived fungi, K. Neumann, S. Kehraus, M. Gütschow, G. M. König, Nat. Prod. Com., 2009, 4, 347-354.

Dietary derived sesquiterpenes from Phyllodesmium lizardensis; S. Affeld, S. Kehraus, H. Wägele, G. M. König, J. Nat. Prod., 2009, 72, 298-300.

Myxotyrosides A and B, unusual rhamnosides from Myxococcus sp.; B. Ohlendorf, W. Lorenzen, S. Kehraus, A. Krick, H. B. Bode, G. M. König, J. Nat. Prod., 2009, 72, 82-86.

 

2008

Phenylnannolones A-C: Biosynthesis of new secondary metabolites from the myxobacterium Nannocystis exedens, B. Ohlendorf,  S. Leyers, A. Krick, S. Kehraus, M. Wiese, G. M. König, ChemBioChem, 2008, 9, 2997-3003.

New peptolides from the cyanobacterium  Nostoc insulare as selective and potent inhibitors of human leukocyte elastase, C. Mehner,  D. Müller, S. Kehraus, S. Hautmann, M. Gütschow, G. M. König, ChemBioChem, 2008, 9, 2692-2703.

Monodictyochromes A and B, dimeric xanthone derivatives from the marine algicolous fungus Monodyctis putredinis, A. Pontius, A. Krick, R. Mesry, S. Kehraus, S. E. Foegen, M. Müller, K. Klimo, C. Gerhäuser, G. M. König, J. Nat. Prod., 2008, 71, 1793-1799.

Noduliprevenone: A novel heterodimeric chromanone with cancer chemopreventive potential, A. Pontius, A. Krick, S. Kehraus, S. E. Foegen, M. Müller, K. Klimo, C. Gerhäuser, G. M. König, Chem. Eur. J., 2008, 32, 9860-9863.

Myxochromide B3, a new member of the myxochromide family of secondary metabolites, B. Ohlendorf, S. Kehraus, G. M. König, J. Nat. Prod., 2008, 71, 1708-1713.

Apralactone A and a new stereochemical class of curvularins from the marine fungus  Curvularia sp., H. Greve,  P. J. Schupp, E. Eguereva, S. Kehraus, G. Kelter, A. Maier, H.-F. Fiebig,  G. M. König, Eur. J. Org. Chem, 2008, 5085-5092.

Antiprotozoal activities of heterocyclic-substituted xanthones from the marine-derived fungus Chaetomium sp., A. Pontius, A. Krick, S. Kehraus, R. Brun, G. M. König, J. Nat. Prod., 2008, 71, 1579-1584.

Ten membered lactones from the marine-derived fungus Curvularia sp., H. Greve, P. J. Schupp, E. Eguereva, G. M. König, J. Nat. Prod., 2008, 71, 1651-1653.

A novel beta-amino acid in cytotoxic peptides from the cyanobacterium  Tychonema sp., C. Mehner,  D. Müller, A. Krick, S. Kehraus, R. Löser, M. Gütschow, A. Maier, H.-F. Fiebig,  R. Brun, G. M. König, Eur. J. Org. Chem, 2008, 1732-1739.

Das Potenzial PCR-basierter Markermethoden zur Identifizierung von Arzneipflanzen, T. Kersten,  C. Daniel, G. M. König, W. Knöß, Zeitschrift für Phytotherapie, 2008, 29, 122-128.

Cytotoxic bastadin 24 from the australian sponge Ianthella quadrangulata, H. Greve, S. Kehraus, A. Krick, G. Kelter, A. Maier, H.-F. Fiebig, A. D. Wright, G. M. König, J. Nat. Prod., 2008, 71, 309-312.

Aromatic polyketides from marine algicolous fungi, A. Pontius, I. Mohamed, A. Krick, S. Kehraus, G. M. König, J. Nat. Prod., 2008, 71, 272-274.

Critical view on the monochlorodimedone assay utilized to detect haloperoxidas activity, C. Wagner, I. M. Molitor, G. M. König, Phytochemistry, 2008, 69, 323-332.

 

2007

Evaluation of quantitative methods for the determination of polyphenols in algal extracts, S. Parys, A. Rosenbaum, S. Kehraus, G. Reher, K.-W. Glombitza, G. M. König, J. Nat. Prod., 2007, 70, 1865-1870.

The chemistry of gliding bacteria, M. Nett, G. M. König, Nat. Prod. Rep. , 2007, 24, 1245-1261.

New Iantherans from the Marine Sponge Ianthella quadrangulata : Novel Agonists of th P2Y11 Receptor, H. Greve, S. Meis, M. U. Kassack, S. Kehraus, A. Krick, A. D. Wright, G. M. König, J. Med. Chem. , 2007, 50, 5600-5607.

Trichothecenes induce accumulation of glycosylceramide in neural cells by interfering with lactosylceramide synthase activity, A. Kralj, M. Gurgui, G. M. König, G. van Echtem-Deckert, Toxicology and Applied Pharmacology, 2007, 225, 113-122.

A marine Mesorhizobium  sp. produces structurally novel long-chain N-acyl-L-homoserine lactones, A. Krick, S. Kehraus, L. Eberl, K. Riedel, H. Anke, I. Kaesler, I. Graeber, U. Szewzyk, G. M. König, Appl. Environ. Microbiol. , 2007, 73, 3587-3594.

Two new depsipeptides from the marine fungus Spicellum roseum , A. Kralj, S. Kehraus, A. Krick, G. van Echten-Deckert, G. M. König, Planta Medica , 2007, 73, 366-371.

Novel sorbicillin derivatives with an unprecedented carbon skeleton from the sponge-derived fungus Trichoderma species , K. Neumann, A. Abdel-Lateff, A. D. Wright, S. Kehraus, A. Krick, G. M. König, Eur. J. Org. Chem. , 2007, 2268-2275.

Potential cancer chemopreventive in vitro activities of monomeric xanthone derivatives from the marine algicolous fungus Monodictys putredinis , A. Krick, S. Kehraus, C. Gerhäuser, K. Klimo, M. Nieger, A. Maier, H.-F. Fiebig, I. Atodiresei, G. Raabe, J. Fleischhauer, G. M. König, J. Nat. Prod. , 2007, 70, 353-360.

Ascospiroketals A and B, unprecedented cycloethers from the marine-derived fungus Ascochyta salicorniae , S. F. Seibert, A. Krick, E. Eguereva, S. Kehraus, G. M. König, Org. Lett. , 2007, 9, 239-242.

 

2006

Natural products from marine organisms and their associated microbes, G. M. König, S. Kehraus, S. F. Seibert, A. Abdel-Lateff, D. Müller, ChemBioChem , 2006, 7, 229-238.

Siphonazol, an unusual metabolite from Herpetosiphon sp.,  M. Nett, Ö. Erol, S. Kehraus, M. Köck, A. Krick, E. Eguereva, E. Neu, G.M. König, Angew. Chem. Int. , 2006, 23, 3863-3867.

Brunsvicamides A-C: Sponge related cyanobacterial peptides with Mycobacterium tuberculosis protein tyrosine phosphatase activity, D. Müller, A. Krick, S. Kehraus, C. Mehner, M. Hart, F.C. Küpper, K. Saxena, H. Prinz, H. Schwalbe, P. Janning, H. Waldmann, G.M. König, J. Med. Chem., 2006, 49, 4871-4878. 
 
Poleketides from marine-derived fungus  Ascochyta salicorniae and their potential to inhibit protein phophatases,  S.F. Seibert, E. Eguereva, A. Krick, S. Kehraus, E. Voloshina, G. Raabe, J. Fleischhauer, E. Leistner, M. Wiese, H. Prinz, K. Alexandrov, P. Janning, H. Waldmann, G.M. König, Org. Biomol. Chem., 2006, 4, 2233-2240.

An attempt to determine the absolute configuration of two ascolactone stereoisomers with time-dependent density functional theory,  S.F. Seibert, G.M. König, E. Voloshina, G. Raabe, J. Fleischhauer, Chirality, 2006, 18, 413-418.

Terpenoids from marine organisms: unique structures and their pharmacological potential, H. Gross, G.M. König, Phytochemistry Reviews, 2006, 5, 115-141. 

Arugosins G and H: Prenylated polyketides from the marine-derived fungus Emericella nidulans var. acristata, A. Kralj, S. Kehraus, A. Krick, E. Eguereva, G. Kelter, M. Maurer, A. Wortmann, H.-H. Fiebig, G.M. König, J. Nat. Prod., 2006, 69, 995-1000. 

Antioxidant activity of 3,4,5-trihydroxybenzaldehyde isolated from Geum japonicum, J.B. Kim, J.B. Kim, G.M. König, A.D. Wright, J. Food Drug Anal., 2006, 14, 190-193. 
 
Effects of cyanobacterium Fischerella ambigua  isolates and cell free culture media on zebra fish (Danio rerio) embryo development, A.D. Wright, O. Papendorf, G.M. König, A. Oberemm, Chemosphere, 2006, 65, 604-608. 


2005

Potentiation of human α4β2 neuronal nicotinic receptors by a Flustra foliacea metabolite, F. Sala, J. Mulet, K.P. Reddy, J.A. Bernal, P. Wikman, L.M. Valor, L.Peters, G.M. König, M. Criado, S. Sala, Neurosc. Lett. 2005, 373, 144-149.

Stereochemical Heterogenity in Verongid Sponge Metabolites. Absolute Stereochemistry of (+)-Fistularin-3 and (+)-11-epi-Fistularin-3 by Microscale LCMS-Marfey’s Analysis, E.W. Rogers, M.F. de Oliveira, R.G.S. Berlinck, G.M. König, T.F. Molinski, J. Nat. Prod., 2005, 68, 891-896.

Ambigol C and 2,4-Dichlorbenzoic Acid, Natural Products Produced by the Terrestrial Cyanobacterium Fischerella ambigua, A.D. Wright, O. Papendorf, G.M. König, J. Nat. Prod. 2005, 68, 459-461.

 

2004

Prenylated Indole Alkaloids from Flustra foliacea with Subtype Specific Binding on NAChRs, L.Peters, A.D. Wright, St. Kehraus, D. Gündisch, M. C. Tilotta, G. M. König, Planta Med., issue dedicated to Prof. Nahrstedt, 2004, 70, 883-886

Isolation and structure elucidation of azoricasterol, a new sterol of the deep water sponge Macandrewia azorica, H. Gross, J. Reitner, G.M. König, Naturwissenschaften, 2004, 91, 441-446.

Novel Amino Acid Derived Natural Products from the Ascidian Atriolum robustum: Identification and pharmacological characterization of a unique adenosine derivative, S. Kehraus, S. Gorzalka, C. Hallmen, J. Igbal, Ch.E. Müller, A.D. Wright, M. Wiese, G.M. König, J. Med. Chem., 2004, 47, 2243-2255.

Translation initiation factor eIF-5A from Plasmodium falciparum, I.M.Molitor, S. Knöbel, Ch. Dang, T. Spielmann, A. Alléra, G.M. König, Mol. Biochem. Parasitol., 2004, 137, 65-74.

New Secondary Metabolites from the Marine Endophytic Fungus Apiospora montagnei, Ch. Klemke, S. Kehraus, A.D. Wright and G.M. König, J. Nat. Prod., 2004, 67, 1058-1063.

Variation of Brominated Indoles and Terpenoids within single and different colonies of the Marine Bryozoan Flustra foliaceae, L. Peters, A.D. Wright, A. Krick and G.M. König, J. Chem. Ecol., 2004, 30, 1165-1181.

Two new bicyclic cembranolides from a new Sarcophyton species and determination of the absolute configuration of sarcoglaucol-16-one, H. Gross, A.D. Wright, W. Beil, and G.M. König, Org. Biomol. Chem., 2004, 2, 1133-1138.

 

2003

Epicoccamide, a Novel Secondary Metabolite from a Jellyfish-Derived Culture of Epicoccum purpurascens, A.D. Wright, C. Osterhage, G. M. König, Org Biomol Chem, 2003, 1, 507-510.

Oxygenated Analogues of Gorgesterol and Ergosterol from the Soft Coral Capnella lacertiliensis, E. Goclik, G. M. König, A. D. Wright, J. Nat. Prod., 2003, 66, 157-160.

New Cytotoxic cembrane based diterpenes from the soft corals Sarcophyton cherbonnieri and Nephthea sp., Groß, H., Kehraus, S., Nett, M., König, G. M., Beil, W., Wright, A. D., Org. Biomol. Chem., 2003, 1, 944-949.

Three New Sesquiterpenes from the Red Alga Laurencia perforata, A. D. Wright, E. Goclik, G. M. König , J. Nat. Prod., 2003, 66, 435-437.

Responses of marine macroalgae to hydrogen-peroxide stress, A.L. Dummermuth, U. Karsten, K. M. Fisch, G. M. König, C. Wiencke, J. Exp. Mar. Biol. Ecol., 2003, 289, 103-121.

Two New Xanthone Derivatives from the Algicolous Marine Fungus Wardomyces anomalus, A. Abdel-Lateff, Ch.
Klemke, G. M. König, A. D. Wright, J. Nat. Prod., 2003, 66 , 706-708.

 

Secondary Metabolites of Flustra foliacea and their influence on bacteria, L. Peters. G. M. König, A. D. Wright, R. Pukall, E. Stackebrandt, L. Eberl, K. Riedel, Appl. Environ. Microbiol., 2003, 69, 3469-3475.

 

Antioxidative Meroterpenoids from the Brown Alga Cystoseira crinita, Katja M. Fisch, Volker Böhm, Anthony D. Wright, Gabriele M. König, J. Nat. Prod., 2003, 66, 968-975.

 

HPLC Isolation of the Antiplasmodially Active Bisbenzylisoquinoline Alkaloids in Cissampelos mucronata Roots, J. Ndaya Tshibangu, A. D. Wright, G. M. König, Phytochem. Anal. 2003, 14 , 13-22. 

  

A New Antioxidant Isobenzofuranone Derivative from the Algicolous Marine Fungus Epicoccum sp., Ahmed Abdel-Lateff, Katja M. Fisch, Anthony D. Wright, Gabriele M. König, Planta Med., 2003, 69, 831-834.

 

2002

A New Cytotoxic Calyculinamide Derivative, Geometricin A, from the Australian Sponge Luffariella geometrica, S. Kehraus, G. M. König, A.D. Wright, J. Nat. Prod. 2002, 65, 1056-1058.

Leucamide A: A New Cytotoxic Heptapeptide from the Australian Sponge Leucetta microraphis, S. Kehraus, G. M. König, A. D. Wright, J. Org. Chem., 2002, 67, 4989-4992.

Evaluation of selected Sudanese medicinal plants for their in vitro activity against hemoflagellates, selected bacteria, HIV-1-RT and tyrosine kinase inhibitory, and for cytotoxicity H. Ali, G.M. König, S.A. Khalid, A.D. Wright, R. Kaminsky, J. Ethnopharmacol., 2002, 83, 219-228

5-Hydroxyramulosin, a New Natural Product Produced by Phoma tropica, a Marine-Derived Fungus from the Alga Fucus spiralis, C. Osterhage, G. M. König, P. G. Jones, A. D. Wright, Planta Med. 2002, 68, 1052-1054.

Rare Sesquiterpenes from the Algicolous Fungus Drechslera dematioidea, C. Osterhage, G. M. König, U. Höller, A. D. Wright, J. Nat. Prod. 2002, 65, 306-313.

Lepadins D-F: Antiplasmodial and Antitrypanosomal Decahydroquinoline Derivatives from the Tropical Marine Tunicate Didemnum sp., A. D. Wright, E. Goclik, G. M. König, R. Kaminsky, J. Med. Chem. 2002, 45, 3067-3072.

Screening of African Medicinal Plants for Antimicrobial and Enzyme Inhibitory Activity, J. Ndaya Tshibangu, K. Chifundera, R. Kaminsky, A. D. Wright, G. M. König, J. Ethnopharmacol., 2002, 80, 25-35.

New Antioxidant Hydroquinone Derivatives from the Algicolous Marine Fungus Acremonium sp., A. Abdel-Lateff, G. M. König, K. M. Fisch, U. Höller, P. Jones, A. D. Wright, J. Nat. Prod., 2002, 65, 1605-1611.

Four New Bromo-tryptamine Derivatives from the Marine Bryozoan Flustra foliacea, L. Peters, G. M. König, H. Terlau, A. D. Wright, J. Nat. Prod., 2002, 65, 1633-1637.

New and Biologically Active Imidazole Alkaloids from two Sponges of the Genus Leucetta, H. Gross, S. Kehraus, G. M. König, G. Wörheide, A. D. Wright, J. Nat. Prod. 2002, 65, 1190-1193.

2001

New Carbonimidic Dichlorides from the Australian sponge Ulosa spongia and their possible taxonomic significance, S. Kehraus, G. M. König and A. D. Wright, J. Nat. Prod., 2001, 64, 939-941.

3-Acetoxyspathulenol, a New Aromadendrane-Type Natural Product from the Soft Coral Parerythropodium fulvum, M. Wessels, G. M. König, A. D. Wright, J. Nat. Prod. 2001, 64, 370-372.

Inhibition of Heme Detoxification Processes underlies the Antimalarial Activity of Terpene Isonitrile Compounds from Marine Sponges, A. D. Wright, H. Wang, M. Gurrath, G. M. König, G. Kocak, G. Neumann, P. Loria, M. Foley, L. Tilley, J. Med. Chem., 2001, 44, 873-885.

New 4-Methoxybenzoyl Derivatives from the Ascidian Polycarpa aurata, M. Wessels, G. M. König, A. D. Wright, J. Nat. Prod. 2001, 64, 1556-1558.

 

 2000

A New Bioactive Sesterterpene and Antiplasmodial Alkaloids from the Marine Sponge Hyrtios cf. erecta, Gesa Kirsch, A. D. Wright, G. M. König, J. Nat. Prod., 2000, 63, 825-829.

New Natural Product Isolation and Comparison of the Secondary Metabolite Content of Three Distinct Samples of the Sea Hare Aplysia dactylomela from Tenerife, M. Wessels, G. M. König and A. D. Wright, J. Nat. Prod., 2000, 63, 920-928.

Assessment of Antimycobacterial Activity of a Series of Mainly Marine Derived Natural Products, G. M. König, A. D. Wright and S. G. Franzblau, Planta Med., 2000, 66, 337-342.

Fungi from Marine Sponges: Diversity Biological Activity and Secondary Metabolites, U. Höller, A. D. Wright, G. F. Matthée, G. M. Konig, S.Draeger, H-. J. Aust, B. Schulz, Mycol. Res., 2000, 104, 1354-1365.

Pelorol from the Tropical Marine Sponge Dactylospongia elegans, E. Goclik, G. M. König and A. D. Wright, J. Nat. Prod., 2000, 63, 1150-1152.

HPLC-DAD and HPLC-MS Investigations of Marine and Terrestrial Phoma Species, C. Wegner, M. Schwibbe, G. M. König and A. D. Wright, Phytochem. Anal., 2000, 11, 288-294.

Ascosalipyrrolidinone A, an Antimicrobial Alkaloid, from the Obligate Marine Fungus Ascochyta salicorniae. C. Wegner, R. Kaminsky, G. M. König, and A. D. Wright, J. Org. Chem., 2000, 65, 6412-6417.

Fungi from marine sponges: diversity, biological activity and secondary metabolites, U. Höller, A. D. Wright, G. F. Matthée, G. M. König, S. Draeger, H.-J. Aust and B. Schulz, Mycol. Res., 2000, 104, 1354-1365.

NMR Spektroskopie, G. M. König, A. D. Wright, in: Analytik biogener Arzneistoffe, Pharmazeutische Biologie, Band 4, H. Becker, K. Adam (eds.), Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, 2000, 37-55.

1999

Geniculol, A New Biologically Active Diterpene from the Endophytic Fungus Geniculosporium sp., G. M. König, A. D. Wright, S. Draeger, H. -J. Aust, B. Schultz, J. Nat. Prod., 1999, 62, 155-157.

Three New Metabolites from Marine Derived Fungi of the Genera Coniothyrium and Microsphaeropsis, U. Höller, G. M. König, A. D. Wright, J. Nat. Prod., 1999, 62, 114-118.

Three New Scalarane Based Sesterterpenes from the Tropical Marine Sponge Strepsichordaia lendenfeldi, T. Jahn, G. M. König, A. D. Wright, J. Nat. Prod., 1999, 62, 375-377.

Halogenated Monoterpenes from Plocamium costatum and their Biological Activity, G. M. König, A. D. Wright and R. de Nys, J. Nat. Prod., 1999, 62, 383-385.

A New Tyrosine Kinase Inhibitor from the Marine Brown Alga Stypopodium zonale, M. Wessels, G. M. König and A. D. Wright, J. Nat. Prod.,1999, 62, 927-930.

Colletoketol, U. Höller, A. D. Wright, G. M. König, P. G. Jones, Acta Cryst., 1999, C55, 1310-1313.

1H and 13C NMR and Biological Activity Investigations of four LIchen Derived Compounds, G. M. König and A. D. Wright, Phytochem. Anal., 1999, 10, 279-284.

Cymbastela hooperi and Amphimedon terpenensis: Where do they really belong? G. M. König and A. D. Wright, Mem. Qd. Mus., 1999 (30 June), 44, 281-288.

Hydrophilic Metabolites from the Tropical Marine Sponge Carteriospongia sp., G. M. König and A. D. Wright, Planta Med., 1999, 65, 679-680.

Plocamium hamatum and Its Monoterpenes: Chemical and Biological Investigations of the Tropical Marine Red Alga, G. M. König, A. D. Wright and A. Linden, Phytochemistry, 1999, 52, 1047-1053.

A New Tyrosine Kinase Inhibitor from a Marine Isolate of Ulocladium botrytis and New Metabolites from the Marine Fungus Asteromyces cruciatus and Varicosporina ramulosa, U. Höller, G. M. König, A. D. Wright, Euro. J. Org. Chem., 1999, 2949-2955.

Collection and Secondary Metabolite Investigations of Marine Organisms from the two Azorean Islands Faial and St. Jorge, E. Goclik, G. M. König and A. D. Wright, Arquipelago, Bulletin of the University of the Azores, Life and Marine Sciences, 1999, 17A, 43-49.

HIV Reverse Transcriptase Inhibitors of Natural Origin, G. Mattee, G. M. König, A. D. Wright, Planta Med., 1999, 65, 493-506.

Trends in Marine Biotechnology, G. M. König, A. D. Wright, in: Drug Discovery in Nature, Grabley, Thiericke (eds.), Springer Verlag, ISBN 64844-5, 1999, 180-187.

1998

An Unprecedented Compound from the Dichloromethane Solubles of the Tropical Marine Sponge Agelas oroides, G. M. König, A. D. Wright, Planta Med., 1998, 64, 88-89.

Three New Diterpenes from the Marine Soft Coral Lobophytum crassum, G. Matthée, G. M. König and A. D. Wright, J. Nat. Prod., 1998, 61, 237-240.

New Cembranoid Diterpenes from the Soft Coral Sarcophyton ehrenbergi, G. M. König and A. D. Wright, J. Nat. Prod., 1998, 61, 494-496.

Antiplasmodial and Cytotoxic Metabolites from the Maltese Sponge Agelas oroides, G. M. König, A. D. Wright and A. Linden, Planta Med., 1998, 64, 443-447.

Hypoglycemic Activity of a HMG-Containing Flavonoid Glucoside from Chamaemelum nobile, G. M. König, A. D. Wright, W. J. Keller, R. L. Judd, and C. Day, Planta Med., 1998, 64, 612-614.

Heirridin B and 2,4-Dimethoxy-6-heptadecyl-phenol, Secondary Metabolites from the Cyanobaterium Phormidium ectocarpi with Antiplasmodial Activity, O. Papendorf, G. M. König, A. D. Wright, Phytochemistry, 1998, 49, 2383-2386.

Sesquiterpene Content of the Antibacterial Dichloromethane Extract of the Marine Red Alga Laurencia obtusa, G. M. König and A. D. Wright, Planta Med., 1997, 63, 186-187.

Secondary Metabolite Investigation of the "Living Fossil" Sponge Astrosclera willeyana, T. Jahn, G. M. König, A. D. Wright, G. Wörheide, J. Reitner, Tetrahedron Lett., 1997, 38, 3883-3884.

Ressource der Zukunft: Wirkstoffe aus marinen Organismen, G. M. König, A. D. Wright, Pharmazeutische Zeitung, 1998, 143, 4153.

 

1997

New and Unusual Sesquiterpenes; Kelsoene, Prespatane, Epi-g-Gurjunene and T-Cadinthiol, from the Tropical Marine Sponge Cymbastela hooperi, G. M. König, A. D. Wright, J. Org. Chem., 1997, 62, 3837-3840.

Pulsed Field Gradient Spectroscopy (PFGS): Application to the Structure Elucidation of (+)-(10S)-10-Bromo-beta-Chamigrene, G. M. König and A. D. Wright, Phytochem. Anal., 1997, 8, 167-172.

Two New Sesterterpene Tetronic Acids from the Marine Sponge Ircinia oros, U. Höller, G. M. König, A. D. Wright, J. Nat. Prod., 1997, 60, 832-835.

Laurencia rigida: Chemical Investigations of its Antifouling Dichloromethane Extract, G. M. König, A. D. Wright, J. Nat. Prod., 1997, 60, 967-970.

Marine and Aquatic Environments: Souces of Novel and Biologically Active Secondary Metabolites, G. M. König and A. D. Wright, Chemica Chronica (General edition), 1997, 59, 106-107.

Mueggelone, a Novel Inhibitor of Fish Development from the Fresh Water Cyanobacterium Aphanizomenon flos aquae, O. Papendorf, G. M. König, A. D. Wright, I. Chorus, A. Oberemm, J. Nat. Prod., 1997, 60, 1298-1300.

Meeresorganismen als Produzenten pharmakologisch aktiver Stoffe, G. M. König, A. D. Wright, Pharmazie in unserer Zeit, 1997, Heft 6, 26. Jahrg., 281.

The Marine Environment: A Source of Novel Antimalarial Lead Structures, G. M. König, A. D. Wright, in: Virtual Activity, Real Pharmacology Different Approaches to the Search for Bioactive Natural Compounds, L. Verotta (ed), Research Signpost, Trivandrum, 1997, 159.

 

1996

Chamaemeloside, a New Flavonoid Glycoside from Chamaemelum anthemis, G. A. Tschan, G. M. König, A. D. Wright and O. Sticher, Phytochemistry, 1996, 41, 643-646.

Novel Potent Antimalarial Diterpene Isocyanates, Isothicyanates, and Isonitriles from the Tropical Marine Sponge Cymbastela hooperi, G. M. König, A. D. Wright, C. K. Angerhofer, J. Org. Chem., 1996, 61, 3259-3267.

Antimalarial Activity: The Search for Marine Derived Natural Products which Demonstrate Selective Antimalarial Activity, A. D. Wright, G. M. König, C. K. Angerhofer, P. Greenidge, A. Linden and R. Desqueyroux-Faundez, J. Nat. Prod., 1996, 59, 710-716.

Cymbastela hooperi n. sp. (Halichondria, Axinellidae) from the Great Barrier Reef, Australia, R. W. M. van Soest, R. Desqueyroux-Faundez, A. D. Wright, G. M. König, Bulletin of the Royal Belgian Institute for Natural Sciences, Biologie, 1996, 66 suppl., 103.

X-Ray Crystal Structure of Amphilectane Derivatives, A. Linden, G. M. König and A. D. Wright, Acta Cryst., 1996, C52, 2601-2607.

Cymbastella hooperi sp. nov. (Halichondrida:Axinellidae) from the Great Barrier Reef, Australia, R. W. M. Van Soest, R. Desqueyroux-Faundez, A. D. Wright and G. M. König, Bull. Inst. R. Sci. Nat. Belg., 1996, 66 suppl., 103-108.

Marine Natural Products Research: Current Directions and Future Potential, G. M. König, A. D. Wright, Planta Med., 1996, 62, 193-211.

 

1995


Two New Naturally Occurring Pyrrole Derivatives from the Tropical Marine Sponge Agelas oroides, G. M. König and A. D. Wright, Nat. Prod. Lett., 1995, 5, 141.

Concerted Application of a Shift Reagent and 2D NOESY to the Structure Determination of New Natural Products from the Tropical Brown Alga Dictyopteris delicatula, G. M. König and A. D. Wright, Magn. Reson. Chem., 1995, 33, 178-183.

Biological Activities of Cyanobacteria: Evaluation of Extracts and Pure Compounds, B. Falch, G. M. König, A. D. Wright, O. Sticher, H. Bachmann, C. K. Angerhofer and J. M. Pezzuto, Planta Med.,1995, 61, 321-328.

Chemical aspects of mass spawning in corals. II.(-)-Epi-thunbergol, the sperm attractant in the eggs of the soft coral Lobophytum crassum (Cnidaria : Octocorallia), J. C. Coll, P. A. Leone, B. F. Bowden, A. R. Carroll, G. M. König, A. Heaton, R. de Nys, M. Maida, P. M. Alino, R. H. Willis, R. C. Babcock, Z. Florian, M. N. Clayton, R. L. Miller, P. N. Alderslade, Mar. Biol., 1995, 123, 137-143.

1H (300MHz) and 13C NMR spectral assignments for diisocyanoadociane, G. M. König, A. D. Wright, Magn. Reson. Chem., 1995, 33, 694-697.

N,N-Dimethyl-1H-pyrrole-2-carboxamide, A. D. Linden, A. D. Wright, G. M. König, Acta Cryst., 1995, C51, 744-747.

Determination of the Absolute Configuration of a Series of Halogenated Furanones from the Marine Red Alga Delisea pulchra, G. M. König, A. D. Wright and G. Bernardinelli, Helv. Chim. Acta, 1995, 78, 758-764.

Studies on the Glycolipid Content of the Cyanobacterium Fischerella ambigua, B. Falch, G. M. König, A. D. Wright, O. Sticher, Planta Med.,1995, 61, 540-543.

 

1994

X-Ray Structure of 3,4-Epoxypalisadin A, G. M. König, A. D. Wright, F. Fronczek, J. Nat. Prod., 1994, 54, 151-154.

Diterpenes from the Brown Alga Dilophus Mediterraneus, C. Goez, A. D. Wright, G. M. König and O. Sticher, Phytochem. Analysis, 1994, 5, 68-73.

Chemical aspects of mass spawning in corals. I. Sperm-attractant molecules in the eggs of the scleractinian coral Montipora digitata, J. C. Coll, B. F. Bowden, G. V. Meehan, G. M. König, A. R. Carroll, D. M. Tapiolas, P. M. Alino, A. Heaton, R. De Nys, P. A. Leone, M. Maida, T. L. Acetet, R. H. Willis, R. C. Babcock, B. L. Willis, Z. Florian, M. N. Clayton, R. L. Miller, Mar. Biol., 1994, 118, 177-182.

Revised Structure of a Brasilane-Type Sesquiterpene isolated from the Red Alga Laurencia implicata and its absolute Configuration, Motoo Tori, Katsuyuki Nakashima, Masashi Seike, Yoshinori Asakawa, A. D. Wright, G. M. König, O. Sticher, Tetrahedron, 1994, 35, 3105-3106.

New Diterpenes from the Tropical Brown Alga Dictyota pardalis f. pseudohamata, G. M. König and A. D. Wright, Tetrahedron, 1994, 50, 8011-8018.

Biological Activities of Selected Marine Natural Products, G. M. König, A. D. Wright, O. Sticher, C. K. Angerhofer, J. M. Pezzuto, Planta Med., 1994, 60, 532-537.

Extensive 1D and 2D NMR and X-Ray Studies of Diterpenes Isolated from the Marine Alga Dictyota pardalis f. pseudohamata, G. M. König, A. D. Wright, F. R. Fronczek, J. Nat. Prod., 1994, 57, 1529-1538.

Hagers Handbuch, 5. Auflage, Band 6, Drogen P - Z, 1994: Monographien über die Gattungen Stevia, Teucrium und Pinguicula, G. M. König, C. Goez.

 

1993

New C15 Acetogenins and Sesquiterpenes from the Marine Red Alga Laurencia sp., c.f., L. gracilis, G. M. König and A. D. Wright, J. Nat. Prod., 1993, 57, 477.

A Diterpene from the Marine Alga Glossophora kunthii, R. de Nys, A. D. Wright, G. M. König, O. Sticher, Phytochemistry, 1993, 32, 463-465.

New and Highly Oxidised Hydroazulenoid Diterpenes from the Tropical Marine Brown Alga Dictyota volubilis, A. D. Wright, G. M. König, O. Sticher, Tetrahedron, 1993, 49, 571-580.

Seven New Metabolites from the Marine Red Alga Laurencia majuscula, A. D. Wright, G. M. König, R. de Nys, O. Sticher, J. Nat. Prod., 1993, 56, 394-401.

Four new hydroazulenoid diterpenes from the tropical marine alga Dictyota volubilis, G. M. König, A. D. Wright, O. Sticher, H. Rüegger, Planta Med., 1993, 59, 174-178.

Agelorins A and B, 11-Epi-Fistularin-3, Three New Antibacterial Fistularin-3 Derivatives from the Tropical Marine Sponge Agelas oroides, G. M. König, A. D. Wright, Heterocycles, 1993, 36, 1351-1359.

Five New Sesquiterpenes from the Tropical Red Alga Laurencia flexilis, R. de Nys, A. D. Wright, G. M. König, O. Sticher, J. Nat. Prod., 1993, 56, 877-883.

Two Metabolites from the Red Alga Laurencia flexilis, R. de Nys, G. M. König, A. D. Wright and O. Sticher, Phytochemistry, 1993, 34, 725-728.

Ambigol A and B: New Biologically Active Polychlorinated Aromatic Compounds from the Terrestrial Blue Green Alga Fischerella ambigua, B. S. Falch, G. M. König, A. D. Wright, H. Rüegger, O. Sticher, G. Bernardinelli, J. Org. Chem., 1993, 58, 6570-6575.

New Halogenated Furanones from the marine alga Delisea pulchra (cf. fimbriata), R. de Nys, A. D. Wright, G. M. König, O. Sticher, Tetrahedron, 1993, 46, 11213-11220.

A New Caryophyllene-based Diterpene from the Soft Coral, Cespitularia species, G. M. König, A. D. Wright, J. Nat. Prod., 1993, 56, 2198-2200.

Algal Secondary Metabolites and their Pharmaceutical Potential, G. M. König, A. D. Wright, in: Human Medicinal Agents from Plants, ACS Symposium Series 534, A. D. Kinghorn, M. F. Balandrin (eds.), Washington DC, 1993, 276.

 

1992

New dolabellane derivatives from the brown alga Dictyota pardalis, A. D. Wright, G. M. König, O. Sticher, P. Lubini, P. Hofmann, M. Dobler, Helv. Chim. Acta, 1992, 74, 1801.

Four new antibacterial sesterterpenes from a marine sponge of the genus Luffariella, G. M. König, A. D. Wright, O. Sticher, J. Nat. Prod., 1992, 55, 174-178.

Two new sesquiterpene isothiocyanates from the marine sponge Acanthella klethra, G. M. König, A. D. Wright, O. Sticher, J. Nat. Prod., 1992, 55, 633-638.

The enhanced role of a lanthanide shift reagent in the structure elucidation, and 1H NMR and 13C NMR characterisation of some marine natural products, A. D. Wright, G. M. König, O. Sticher, Phytochem. Anal., 1992, 3, 73-79.

A diterpene from Dictyota bartayresii, G. M. König, A. D. Wright, R. de Nys, O. Sticher, Phytochemistry, 1992, 31, 2541-2542.

The Application of Two-dimensional Nuclear Magnetic Resonance Methodologies to the Structure Solution of the New Natural Product Tenerol Acetate from Laurencia tenera, A. D. Wright, G. M. König, O. Sticher, H. Rüegger, Phytochem. Anal., 1992, 3, 263-269.

Antimalarial Sesquiterpenes from the Marine Sponge Acanthella klethra, C. K. Angerhofer, G. M. König, A. D. Wright, O. Sticher, J. M. Pezzuto, J. Nat. Prod., 1992, 55, 1787-1789.

Naturstoffe aus Meeresorganismen und höheren Pflanzen, G. M. König, A. D. Wright, S. M. Oechslin, O. Sticher, Vierteljahrsschrift der Naturforschenden Gesellschaft in Zürich, 1992, 137, 207.

Meeresorganismen als Quelle pharmazeutisch bedeutsamer Naturstoffe, G. M. König, Deutsche Apotheker Zeitung, 1992, 132, 673.

Selective screening of natural products: a resource for the discovery of novel antimalarial compounds, C. K. Angerhofer, G. M. König, A. D. Wright, O. Sticher, W. K. Milhous, G. A. Cordell, N. R. Farnsworth, J. M. Pezzuto, in Advances in Natural Products Chemistry, Atta-ur-Rahman (ed.), Harwood Academic Publishers GmbH, 1992, 311.

 

1991


New Xenicane and Hydroazulenoid Diterpenes from an Australian collection of Dictyota divaricata, G. M. König, A. D. Wright, O. Sticher, Tetrahedron, 1991, 47, 1399-1410.

An NMR Study of four Benzophenanthridine Alkaloids, S. M. Oechslin, G. M. König, K. Oechslin-Merkel, A. D. Wright, A. D. Kinghorn, O. Sticher, J. Nat. Prod., 1991, 54, 519-524.

Diterpenes from the brown alga Dictyota divaricata, G. M. König, A. D. Wright, O. Sticher, Phytochemistry, 1991, 30, 3679-3682.

Five new monoterpenes from the marine red alga Portieria hornemannii, A. D. Wright, G. M. König, O. Sticher, R. de Nys, Tetrahedron, 1991, 47, 5717-5724.

New sesquiterpenes and C15 acetogenins from the marine red alga Laurencia implicata, A. D. Wright, G. M. König, O. Sticher, J. Nat. Prod., 1991, 54, 1025-1033.

New planar chromatographic techniques in natural product analysis, C. A. J. Erdelmeier, G. M. König, Phytochem. Analysis, 1991, 2, 3.

 

1990

A new polyhalogenated monoterpene from the red alga Plocamium cartilagineum, G. M. König, A. D. Wright, O. Sticher, J. Nat. Prod., 1990, 53, 1615-1618.

Two new dolabellane derivatives from the brown alga Dictyota pardalis, A. D. Wright, G. M. König, O. Sticher, Tetrahedron, 1990, 46, 3851-3858.

New Briaran Diterpenoids from the Gorgonian Coral Junceela gemmacea, B. F. Bowden, J. C. Coll, G. M. König, Australian Journal of Chemistry, 1990, 43, 151.

 

1989

Chemically mediated interactions between marine organisms, J. C. Coll, B. F. Bowden, P. M. Alino, A. Heaton, G. M. König, R. de Nys, R. H. Willis, P. W. Sammarco, M. N. Clayton, Chemica Scripta, 1989, 29, 383.

The Structure Determination of a Xenicane Diterpene from Xenia garciae, G. M. König, J. C. Coll, B. F. Bowden, J. C. Gulbis, M. F. Mac Kay, S. C. La Barre, D. Laurent, J. Nat. Prod., 1989, 52, 294-299.

 

1987

The structures of four isomeric dihydrofuran containing cembranoid diterpenes from several species of soft corals, B. F. Bowden, J. C. Coll, A. Heaton, G. M. König, M. A. Bruck, R. E. Cramer, D. E. Klein, P. J. Scheuer, J. Nat. Prod., 1987, 50, 650-659.

Algal overgrowth of alcyonacean soft corals, J. C. Coll, I. R. Price, G. M. König, B. F. Bowden, Mar. Biol., 1987, 96, 129. 

Iridoid glucosides in Avicennia officinalis, G. M. König, H. Rimpler, D. Hunkler, Phytochemistry, 1987, 26, 423-427.

 

1986

The natural products chemistry of alcyonacean soft corals with special reference to the genus Lobophytum, J. C. Coll, B. F. Bowden, G. M. König, R. Braslau, Bull. Soc. Chim. Belg., 1986, 95, 815.

Iridoid glucosides in Avicennia marina, Phytochemistry, G. M. König, H. Rimpler, 1985, 24, 1245.

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